Journal Published Online: 01 March 1987
Volume 32, Issue 2

Central Pontine Myelinolysis: A Complication of Hyponatremia or of Therapeutic Intervention?

CODEN: JFSCAS

Abstract

We report four cases of central pontine myelinolysis (CPM) that illustrate important features of the disorder. The condition is described mainly in the neurological literature and, to our knowledge, is not discussed in the forensic science journals. This disorder must be recognized and understood by the forensic science expert who addresses issues of liability. In cases of multiple motor deficits and death with a history of hyponatremia, CPM must be included in the differential diagnosis. Careful examination of the pons and adjoining structures must be performed. Myelin stains are advisable. The association of CPM with major illnesses, hyponatremia and the correction of hyponatremia by intravenous saline infusions is discussed.

Author Information

Haibach, H
University of Missouri-Columbia, School of Medicine, Columbia, MO
Ansbacher, LE
University of Missouri-Columbia, School of Medicine, Columbia, MO
Dix, JD
University of Missouri-Columbia, School of Medicine, Columbia, MO
Pages: 8
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Stock #: JFS11146J
ISSN: 0022-1198
DOI: 10.1520/JFS11146J