Volume 30, Issue 4 (October 1985)

    Effect of Sodium Fluoride on Cholinesterase Activity in Postmortem Blood

    (Received 21 December 1984; accepted 29 January 1985)

    Published Online: October

    CODEN: JFSOAD

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    Abstract

    Thirty-two postmortem blood specimens, with and without sodium fluoride as preservative, were analyzed for cholinesterase activity by the Michel method. The fluoridated specimens, which contained from 0.7 to 31 mg/mL (average 6.3) of sodium fluoride, were found to exhibit cholinesterase activities that were 5 to 59% (average 25%) lower than the duplicate unfluoridated specimens. We concluded that, while this decrease is quite significant, a fluoridated post-mortem blood specimen may be used for the measurement of cholinesterase activity when a non-fluoridated specimen is unavailable.


    Author Information:

    Baselt, RC
    Director, Chemical Toxicology Institute, Foster City, CA

    Shaw, RF
    Chief toxicologist and assistant toxicologist, Office of the Coroner, San Diego, CA

    McEvilly, R
    Chief toxicologist and assistant toxicologist, Office of the Coroner, San Diego, CA


    Stock #: JFS11061J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11061J

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    Author
    Title Effect of Sodium Fluoride on Cholinesterase Activity in Postmortem Blood
    Symposium , 0000-00-00
    Committee E30