Journal Published Online: 01 October 1985
Volume 30, Issue 4

Effect of Sodium Fluoride on Cholinesterase Activity in Postmortem Blood

CODEN: JFSCAS

Abstract

Thirty-two postmortem blood specimens, with and without sodium fluoride as preservative, were analyzed for cholinesterase activity by the Michel method. The fluoridated specimens, which contained from 0.7 to 31 mg/mL (average 6.3) of sodium fluoride, were found to exhibit cholinesterase activities that were 5 to 59% (average 25%) lower than the duplicate unfluoridated specimens. We concluded that, while this decrease is quite significant, a fluoridated post-mortem blood specimen may be used for the measurement of cholinesterase activity when a non-fluoridated specimen is unavailable.

Author Information

Baselt, RC
Chemical Toxicology Institute, Foster City, CA
Shaw, RF
Office of the Coroner, San Diego, CA
McEvilly, R
Office of the Coroner, San Diego, CA
Pages: 4
Price: $25.00
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Stock #: JFS11061J
ISSN: 0022-1198
DOI: 10.1520/JFS11061J