Volume 30, Issue 4 (October 1985)

    Retrieval of Analytical Data and Substance Identification in Systematic Toxicological Analysis by the Mean List Length Approach

    (Received 15 October 1984; accepted 3 March 1985)

    Published Online: October

    CODEN: JFSOAD

      Format Pages Price  
    PDF Version 8 $25   ADD TO CART


    Abstract

    Chromatographic techniques are basic tools in systematic toxicological analysis. Extensive data bases with retention parameters of known drugs to aid in the identification of substances found are available or in preparation. For a search in such a data base the computer is indispensable. The commonly used window search has some disadvantages which can be overcome by a search based on the statistical concept, the mean list length. The latter retrieval system gives for each candidate in the identification process a probability value. It is shown that these probability values are highly influenced by the reproducibility of the retention parameters of the analytical systems used. Explanations for these phenomena are given.


    Author Information:

    Franke, J-P
    Senior research associate, professor of toxicology, and research associate, State University, Groningen,

    Schepers, PGAM
    Senior research associate, professor of toxicology, and research associate, State University, Groningen,

    de Zeeuw, RA
    Senior research associate, professor of toxicology, and research associate, State University, Groningen,


    Stock #: JFS11048J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11048J

    ASTM International
    is a member of CrossRef.

    Author
    Title Retrieval of Analytical Data and Substance Identification in Systematic Toxicological Analysis by the Mean List Length Approach
    Symposium , 0000-00-00
    Committee E30