Postmortem Biochemical Changes in Canine Vitreous Humor

    Volume 25, Issue 1 (January 1980)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 January 1980

    Page Count: 7


    Strafuss, AC
    Veterinary pathologists, College of Veterinary Medicine, Kansas State University, Manhattan,

    Schoning, P
    Veterinary pathologists, College of Veterinary Medicine, Kansas State University, Manhattan,

    (Received 19 May 1979; accepted 31 July 1979)

    Abstract

    Time and temperature effects on postmortem vitreous humor from 60 adult mongrel dogs were studied. After death the dogs were held at 4, 20, or 37° for intervals of 3, 6, 12, 24, or 48 h. Antemortem and postmortem vitreous was analyzed for sodium, chloride, potassium, urea nitrogen, glucose, and creatinine. Potassium levels rose with increases in temperature and time. Sodium, chloride, and urea nitrogen values were stable at 4° for 48 h; they were less stable at higher temperatures. Glucose dropped to less than half within 3 h at all temperatures. Creatinine values were inconsistent. In that postmortem glucose and sodium levels remained below antemortem levels, diagnosis of hyperglycemia and hypernatremia should be possible. Consequently, a diagnosis of hypoglycemia could not be supported; the diagnosis of hyponatremia could be made in the early postmortem period.


    Paper ID: JFS10936J

    DOI: 10.1520/JFS10936J

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    Title Postmortem Biochemical Changes in Canine Vitreous Humor
    Symposium , 0000-00-00
    Committee E30