The Rapid Determination of Cocaine and Other Local Anesthetics Using Field Tests and Chromatography

    Volume 24, Issue 4 (October 1979)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 October 1979

    Page Count: 9


    Baker, PB
    Senior scientific officer and head of Regulated Drugs Subdivision, Laboratory of the Government Chemist, London,

    Gough, TA
    Senior scientific officer and head of Regulated Drugs Subdivision, Laboratory of the Government Chemist, London,

    (Received 26 February 1979; accepted 11 May 1979)

    Abstract

    Cocaine, which is obtained from the leaves of plants of the genus Erythroxylon, either directly or by chemical transformation, has been used throughout recorded history because of its local anesthetic activity [1]. As a result of its undesirable side effects its use is now controlled almost worldwide. The search for alternative compounds having topical or local anesthetic properties without the inherent disadvantage in using cocaine resulted in the synthesis of a number of satisfactory alternatives to cocaine.


    Paper ID: JFS10913J

    DOI: 10.1520/JFS10913J

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    Title The Rapid Determination of Cocaine and Other Local Anesthetics Using Field Tests and Chromatography
    Symposium , 0000-00-00
    Committee E30