Journal Published Online: 01 October 1979
Volume 24, Issue 4

Increased Safety and Specificity in the Thin-Layer Chromatographic Identification of Marihuana

CODEN: JFSCAS

Abstract

An in-depth study of alleged false positives in the chemical identification of marihuana has previously been reported [1]. Subsequent to publication of that paper, two health and safety considerations have come to our attention. Fast Blue B (3,3′-dimethoxybiphenyl 4,4′-bisdiazonium chloride) is suspected of being carcinogenic [2] because of the presence of unreacted amines, which are known carcinogens [3]. More importantly, benzene, which is the major component in the thin-layer chromatographic (TLC) system [1], has now been conclusively established as a carcinogen. The Occupational Safety and Health Administration (OSHA) has issued an emergency temporary standard because a grave danger exists for workers exposed to benzene. Because of the danger and stringent regulations [4] it was decided to discontinue the use of benzene.

Author Information

Hughes, RB
Mid-Atlantic Regional Laboratory, Washington, D.C.
Kessler, RR
Mid-Atlantic Regional Laboratory, Washington, D.C.
Pages: 5
Price: $25.00
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Stock #: JFS10912J
ISSN: 0022-1198
DOI: 10.1520/JFS10912J