ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 October 1979
Page Count: 5

Increased Safety and Specificity in the Thin-Layer Chromatographic Identification of Marihuana
Hughes, RB
Forensic chemists, Mid-Atlantic Regional Laboratory, D.C.

Kessler, RR
Forensic chemists, Mid-Atlantic Regional Laboratory, D.C.

(Received 6 February 1979; accepted 19 March 1979)

Abstract

An in-depth study of alleged false positives in the chemical identification of marihuana has previously been reported [1]. Subsequent to publication of that paper, two health and safety considerations have come to our attention. Fast Blue B (3,3′-dimethoxybiphenyl 4,4′-bisdiazonium chloride) is suspected of being carcinogenic [2] because of the presence of unreacted amines, which are known carcinogens [3]. More importantly, benzene, which is the major component in the thin-layer chromatographic (TLC) system [1], has now been conclusively established as a carcinogen. The Occupational Safety and Health Administration (OSHA) has issued an emergency temporary standard because a grave danger exists for workers exposed to benzene. Because of the danger and stringent regulations [4] it was decided to discontinue the use of benzene.

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Paper ID: JFS10912J
DOI: 10.1520/JFS10912J
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