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    Volume 24, Issue 2 (April 1979)

    Hereditary Angioneurotic Edema: An Unusual Case of Maternal Mortality

    (Received 28 June 1978; accepted 7 August 1978)

    Published Online: April

    CODEN: JFSOAD

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    Abstract

    Hereditary angioneurotic edema is an autosomal dominant, nonallergic disorder characterized by recurrent attacks of brawny edema of the extremities, face, larynx, and genitalia [1] and biochemically by a reduction in the serum protein C1 esterase inhibitor, a factor which prevents the activation of the first component of the complement system [2]. Although most attacks are precipitated by trauma [3], there have been no previously reported cases in pregnancy during delivery or in the immediate postpartum period, despite obvious traumatic injury during the birth process. This report describes a patient who, following delivery, developed localized perineal swelling, which over 72 h progressed to generalized edema, terminating in irreversible shock.


    Author Information:

    Postnikoff, IM
    Resident, Mount Sinai Hospital,

    Pritzker, KPH
    Resident, Mount Sinai Hospital,


    Stock #: JFS10855J

    ISSN: 0022-1198

    DOI: 10.1520/JFS10855J

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    Author
    Title Hereditary Angioneurotic Edema: An Unusual Case of Maternal Mortality
    Symposium , 0000-00-00
    Committee E30