Journal Published Online: 01 April 1979
Volume 24, Issue 2

Hereditary Angioneurotic Edema: An Unusual Case of Maternal Mortality

CODEN: JFSCAS

Abstract

Hereditary angioneurotic edema is an autosomal dominant, nonallergic disorder characterized by recurrent attacks of brawny edema of the extremities, face, larynx, and genitalia [1] and biochemically by a reduction in the serum protein C1 esterase inhibitor, a factor which prevents the activation of the first component of the complement system [2]. Although most attacks are precipitated by trauma [3], there have been no previously reported cases in pregnancy during delivery or in the immediate postpartum period, despite obvious traumatic injury during the birth process. This report describes a patient who, following delivery, developed localized perineal swelling, which over 72 h progressed to generalized edema, terminating in irreversible shock.

Author Information

Postnikoff, IM
University of Toronto, Canada
Pritzker, KPH
University of Toronto, Canada
Pages: 6
Price: $25.00
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Stock #: JFS10855J
ISSN: 0022-1198
DOI: 10.1520/JFS10855J