Volume 24, Issue 2 (April 1979)
Incidence of Cocaine Metabolites in Urine Specimens from Medical Examiners' Cases
In their recent report on the toxicology and epidemiology of cocaine, Finkle and McCloskey summarized data from 27 medical examiners' offices . Methods used by the contributing laboratories varied widely in sensitivity and specificity and included thin-layer chromatography, gas-liquid chromatography, mass spectrometry, spectrophotometry, radioimmunoassay, and enzyme-linked immunoassay. The sensitivity range generally reported by participating laboratories was 1 to 2 μg/ml cocaine. Sixteen laboratories relied on detecting only parent cocaine, while eleven laboratories also analyzed for benzoylecgonine, the principal cocaine metabolite.