ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 January 1979
Page Count: 6

Determination at the Nanogram Range of Rilatinic Acid in Urine After Ion-Pair Extraction
Van Boven, M
Chemist and director, Laboratory of Toxicology, University of Louvain,

Daenens, P
Chemist and director, Laboratory of Toxicology, University of Louvain,

(Received 30 March 1978; accepted 9 May 1978)

Abstract

Methylphenidate (α-phenyl-2-piperidineacetic acid methyl ester), synthetized by Panizzon [1], is a central nervous system stimulant of the amphetamine series. It differs from many of the phenylisopropylamines in having moderate effects on the peripheral circulatory system. It is used in the management of hyperkinetic and perceptually handicapped children [2] where it is claimed to improve both behavior and learning ability [3]. It is not only a doping agent for sportsmen but also an increasing factor in the drug abuse problem. In many countries this drug has been submitted to narcotic regulations.

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Paper ID: JFS10789J
DOI: 10.1520/JFS10789J
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