Volume 23, Issue 2 (April 1978)
Determination of Group Specific Component Phenotypes in Dried Bloodstains by Immunofixation on Cellulose Acetate
A rapid method is described for the determination of the genetically controlled group specific component (Gc) system. The method uses electrophoresis on cellulose acetate membranes followed by immunofixation with a specific anti-Gc antiserum. The method has been successfully applied to samples of plasma, whole blood, and dried bloodstains. Multiple specimens, up to 16 samples, can be analyzed simultaneously in a total analysis time of less than 60 min. In contrast to conventional immunoelectrophoresis on agar gel, or immunofixation on agarose or starch gel , this method of immunofixation on cellulose acetate is rapid, reliable, and economical.