ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 April 1978
Page Count: 6

Correlation of Antemortem and Postmortem Digoxin Levels
Coe, JI
Chief of pathology, Hennepin County Medical Center, Minn.

Vorpahl, TE
Pathologist, St. Paul-Ramsey Hospital, Minn.

(Received 25 July 1977; accepted 16 September 1977)

Abstract

The dynamics of digoxin metabolism have been well studied since the introduction of sensitive radioimmunoassay procedures capable of detecting low biologic levels of this compound [1]. The value of monitoring digoxin therapy through serum levels has been widely accepted, and toxic effects are frequently observed when the serum level of adult individuals exceeds 2 ng/ml [2,3]. Beller et al [4] reported a twofold increase in mortality among hospitalized patients having digitalis toxicity.

Keywords:

Paper ID: JFS10764J
DOI: 10.1520/JFS10764J
ASTM International is a member of CrossRef.