Correlation of Antemortem and Postmortem Digoxin Levels

    Volume 23, Issue 2 (April 1978)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 April 1978

    Page Count: 6


    Coe, JI
    Chief of pathology, Hennepin County Medical Center, Minneapolis, Minn.

    Vorpahl, TE
    Pathologist, St. Paul-Ramsey Hospital, St. Paul, Minn.

    (Received 25 July 1977; accepted 16 September 1977)

    Abstract

    The dynamics of digoxin metabolism have been well studied since the introduction of sensitive radioimmunoassay procedures capable of detecting low biologic levels of this compound [1]. The value of monitoring digoxin therapy through serum levels has been widely accepted, and toxic effects are frequently observed when the serum level of adult individuals exceeds 2 ng/ml [2,3]. Beller et al [4] reported a twofold increase in mortality among hospitalized patients having digitalis toxicity.


    Paper ID: JFS10764J

    DOI: 10.1520/JFS10764J

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    Author
    Title Correlation of Antemortem and Postmortem Digoxin Levels
    Symposium , 0000-00-00
    Committee E30