Volume 23, Issue 4 (October 1978)
Determination of Serum Myoglobin Level After Death in the Diagnosis of Sudden Coronary Artery Occlusion
Toxicologic studies have become standard procedure in the investigation of medicolegal deaths and some biochemical parameters in the cadaver's blood may be useful in validating autopsy findings . In our experience, the determination of lactic dehydrogenase (LDH), creatine phosphokinase (CPK), and glutamic oxalacetic transaminase (GOT) in serum has been useful in the evaluation of cardiac death when this occurs several hours to a few days after the occurrence of the cardiac catastrophe. However, the enzymatic cardiac parameters are of little impact when death occurs suddenly in apparently healthy individuals and acute coronary occlusion is the cause of death, since they do not show significant enough changes.