Journal Published Online: 01 July 1977
Volume 22, Issue 3

Forensic Applications of X-Ray Diffraction. I: Differentiation of Piperidyl Benzilates and Related Glycolates by Micro-X-Ray Diffraction

CODEN: JFSCAS

Abstract

The differentiation of closely related compounds is a subject of considerable forensic importance, especially for drugs where relatively minor compositional or structural variations, such as different substituents or isomerism, have considerable physiological effects and may distinguish between a controlled substance and an uncontrolled one. Frequently, common techniques such as ultraviolet (UV) spectroscopy are ineffective in such cases [1], and others such as thin-layer chromatography (TLC) [2] lack specificity of response. Some effective techniques such as mass spectrometry (MS) [3] are often not readily available.

Author Information

Barrick, JC
Institute of Chemical Analysis, Applications and Forensic Science, Northeastern University, Boston, Mass.
Polk, DE
Institute of Chemical Analysis, Applications and Forensic Science, Northeastern University, Boston, Mass.
Raman, RV
Institute of Chemical Analysis, Applications and Forensic Science, Northeastern University, Boston, Mass.
Giessen, BC
Institute of Chemical Analysis, Applications and Forensic Science, Northeastern University, Boston, Mass.
Pages: 9
Price: $25.00
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Stock #: JFS10622J
ISSN: 0022-1198
DOI: 10.1520/JFS10622J