Forensic Applications of X-Ray Diffraction. I: Differentiation of Piperidyl Benzilates and Related Glycolates by Micro-X-Ray Diffraction

    Volume 22, Issue 3 (July 1977)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 July 1977

    Page Count: 9


    Giessen, BC
    Research associate, senior scientist, research assistant, and associate director, Institute of Chemical Analysis, Applications and Forensic Science, Northeastern University, Boston, Mass.

    Polk, DE
    Research associate, senior scientist, research assistant, and associate director, Institute of Chemical Analysis, Applications and Forensic Science, Northeastern University, Boston, Mass.

    Barrick, JC
    Research associate, senior scientist, research assistant, and associate director, Institute of Chemical Analysis, Applications and Forensic Science, Northeastern University, Boston, Mass.

    Raman, RV
    Research associate, senior scientist, research assistant, and associate director, Institute of Chemical Analysis, Applications and Forensic Science, Northeastern University, Boston, Mass.

    (Received 22 November 1976; accepted 11 January 1977)

    Abstract

    The differentiation of closely related compounds is a subject of considerable forensic importance, especially for drugs where relatively minor compositional or structural variations, such as different substituents or isomerism, have considerable physiological effects and may distinguish between a controlled substance and an uncontrolled one. Frequently, common techniques such as ultraviolet (UV) spectroscopy are ineffective in such cases [1], and others such as thin-layer chromatography (TLC) [2] lack specificity of response. Some effective techniques such as mass spectrometry (MS) [3] are often not readily available.


    Paper ID: JFS10622J

    DOI: 10.1520/JFS10622J

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    Title Forensic Applications of X-Ray Diffraction. I: Differentiation of Piperidyl Benzilates and Related Glycolates by Micro-X-Ray Diffraction
    Symposium , 0000-00-00
    Committee E30