Comparative Studies on the Rate of Ethanol Elimination in Acute Poisoning and in Controlled Conditions

    Volume 22, Issue 2 (April 1977)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 April 1977

    Page Count: 6


    Pach, J
    Clinical toxicologists, Institute of Internal Medicine, Academy of Medicine, Krakow,

    Bogusz, M
    Head, Institute of Forensic Medicine, Academy of Medicine, Krakow,

    Staśko, W
    Clinical toxicologists, Institute of Internal Medicine, Academy of Medicine, Krakow,

    (Received 14 June 1976; accepted 13 September 1976)

    Abstract

    For many years, a view has been established in toxicology that the elimination of ethanol in the blood is by zero-order kinetics, that is, at a constant rate [1ߝ5]. A factor which restricts ethanol metabolism is the reoxidation of a reduced form of nicotinamide dinucleotide (NADH) produced during ethanol oxidation to acetaldehyde by an alcohol dehydrogenase (ADH)-NADH system [6,7].


    Paper ID: JFS10608J

    DOI: 10.1520/JFS10608J

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    Title Comparative Studies on the Rate of Ethanol Elimination in Acute Poisoning and in Controlled Conditions
    Symposium , 0000-00-00
    Committee E30