ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 April 1977
Page Count: 6

Comparative Studies on the Rate of Ethanol Elimination in Acute Poisoning and in Controlled Conditions
Pach, J
Clinical toxicologists, Institute of Internal Medicine, Academy of Medicine,

Bogusz, M
Head, Institute of Forensic Medicine, Academy of Medicine,

Staśko, W
Clinical toxicologists, Institute of Internal Medicine, Academy of Medicine,

(Received 14 June 1976; accepted 13 September 1976)

Abstract

For many years, a view has been established in toxicology that the elimination of ethanol in the blood is by zero-order kinetics, that is, at a constant rate [1ߝ5]. A factor which restricts ethanol metabolism is the reoxidation of a reduced form of nicotinamide dinucleotide (NADH) produced during ethanol oxidation to acetaldehyde by an alcohol dehydrogenase (ADH)-NADH system [6,7].

Keywords:

Paper ID: JFS10608J
DOI: 10.1520/JFS10608J
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