Volume 21, Issue 3 (July 1976)
Identification of Drugs and Other Toxic Compounds from Their Ultraviolet Spectra. Part III: Ultraviolet Absorption Properties of 22 Structural Groups
This paper concludes a series of three papers which present ultraviolet (UV) absorption data of drugs and toxic organic compounds systematically by grouping according to chemical structure. As in Parts I and II [1,2], structural groups are spectrophotometrically characterized by (1) an absorption profile which is a graph of wavelength versus absorbance from 200 to 340 rim, (2) the effect of pH change, (3) the effect of decreased solvent polarity relative to water, and (4) the intensity of the absorption bands. The purposes of this series are first, to aid in rapidly characterizing an unknown organic compound from UV data and second, to interpret UV spectra in terms of chemical structure. An analyst in a forensic situation should be able to defend an identification on the basis that a given molecular structure is specifically indicated by the tests conducted. Understanding the specificity of each test leads the analyst to more clear-cut decisions in establishing an identification with the degree of scientific certainty expected of him. Reviews and pertinent publications related to this presentation have been cited in Parts I and II [1,2].