ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 July 1976
Page Count: 7

Antemortem Conversion of Codeine to Morphine in Man
Griesemer, EC
Head toxicologist, supervising toxicologist, and chief medical examiner-coroner, Calif.

Nakamura, GR
Head toxicologist, supervising toxicologist, and chief medical examiner-coroner, Calif.

Noguchi, TT
Head toxicologist, supervising toxicologist, and chief medical examiner-coroner, Calif.

(Received 20 October 1975; accepted 25 November 1975)

Abstract

In the routine screening of postmortem specimens in this laboratory, whenever codeine is detected, morphine is almost always found concurrently. Adler [1] and Mannering et al [2] demonstrated that, in man, codeine is demethylated to morphine, and that as much as 17.2% of codeine appears as bound and unbound morphine in urine.

Keywords:

Paper ID: JFS10525J
DOI: 10.1520/JFS10525J
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