Volume 21, Issue 3 (July 1976)
Studies by Crossed Electroimmunodiffusion on the Individuality and Sexual Origin of Bloodstains
The potential value of serologic reactions to forensic studies has been recognized since 1901 when Uhlenhuth  used the precipitin test to distinguish human from animal blood and Landsteiner  used agglutination to show ABO antigenic differences among human red blood cells (RBC). However, the successful use of serologic techniques in criminal cases did not occur until 1916 when Lattes  devised a simple agglutination test for ABO typing of human bloodstains. The Lattes test, though widely used in the past and improved in various ways [4ߝ9], is no longer the method of choice in most forensic laboratories because positive results depend on preservation of the activity of relatively labile antibodies in the stain.