Application of Allergy Diagnosis in Forensic Serology

    Volume 22, Issue 4 (October 1977)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 October 1977

    Page Count: 8


    Werrett, DJ
    Higher scientific officer and senior scientific officer, Home Office Central Research Establishment, Aldermaston, Reading, Berkshire

    King, LA
    Higher scientific officer and senior scientific officer, Home Office Central Research Establishment, Aldermaston, Reading, Berkshire

    (Received 17 January 1977; accepted 28 March 1977)

    Abstract

    The general approach to the characterization of bloodstains by “antibody profiling” has been described earlier [1]. Antibodies are produced by an individual against foreign organic matter (antigens). As each antibody is designed to react with a specific antigen, a study of the types of antibody present in a person's blood may provide information about that individual's past health record. The use of the Radio-Allergo-Sorbent-Test (RAST®) to measure allergy-associated antibodies in dried blood has also been described earlier [2,3]. These IgE antibodies are detected by incubation of bloodstain extracts with purified allergen coupled to small paper disks. It has been shown that at least three different allergen disks could be incubated simultaneously in a bloodstain extract made from less than 50 μl of whole blood [3].


    Paper ID: JFS10416J

    DOI: 10.1520/JFS10416J

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    Author
    Title Application of Allergy Diagnosis in Forensic Serology
    Symposium , 0000-00-00
    Committee E30