Volume 22, Issue 4 (October 1977)
Application of Allergy Diagnosis in Forensic Serology
The general approach to the characterization of bloodstains by “antibody profiling” has been described earlier . Antibodies are produced by an individual against foreign organic matter (antigens). As each antibody is designed to react with a specific antigen, a study of the types of antibody present in a person's blood may provide information about that individual's past health record. The use of the Radio-Allergo-Sorbent-Test (RAST®) to measure allergy-associated antibodies in dried blood has also been described earlier [2,3]. These IgE antibodies are detected by incubation of bloodstain extracts with purified allergen coupled to small paper disks. It has been shown that at least three different allergen disks could be incubated simultaneously in a bloodstain extract made from less than 50 μl of whole blood .