Volume 21, Issue 1 (January 1976)
Determination of Fluoride by Specific Ion Electrode and Report of a Fatal Case of Fluoride Poisoning
Postmortem fluoride levels in fluoride poisoning cases can be measured conveniently with the specific ion or ion-sensitive electrode. Earlier techniques commonly used complexing agents and depended on colorimetric quantitation [1–6]. Separation of fluoride from the postmortem specimens was achieved by several means including microdiffusion [3–6]. The specific ion electrode measurement of fluoride has been employed directly in urine and other fluids and after separation of the fluoride from biological specimens [6–10]. The subjects of this report are a method combining microdiffusion as a separation procedure with specific ion electrode quantitation of fluoride and the results obtained from a case in which this method was used.