Quantitative Extraction of Tubocurarine, Gallamine, and Decamethonium from Biological Materials

    Volume 20, Issue 1 (January 1975)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 January 1975

    Page Count: 5


    Wittmer, D
    Research associate, School of Pharmacy, University of Missouri, Kansas City, Mo.

    Atwell, S
    Laboratory supervisor, Toxicology Laboratory, The Childrens Mercy Hospital, Kansas City, Mo.

    Haney, WG
    Assistant professor of pharmaceutical chemistry, School of Pharmacy, University of Missouri, Kansas City, Mo.

    (Received 22 April 1974; accepted 8 June 1974)

    Abstract

    Forensic analysis of skeletal muscle relaxants such as tubocurarine and gallamine has been hampered by the fact that these quaternary ammonium compounds are not readily extractable from the biological matrix. Several techniques have been presented to effect this extraction, but these appear to result in either erratic, incomplete extraction [1] or in nonselective extraction [2].


    Paper ID: JFS10243J

    DOI: 10.1520/JFS10243J

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    Title Quantitative Extraction of Tubocurarine, Gallamine, and Decamethonium from Biological Materials
    Symposium , 0000-00-00
    Committee E30