Anaphylactic Deaths: A Clinicopathologic Study of 43 Cases

    Volume 17, Issue 4 (October 1972)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Page Count: 16


    Delage, C
    Associate pathologist and chief, Registry of Tissue Reactions to Drugs, Armed Forces Institute of Pathology, Washington, D.C.

    Irey, NS
    Associate pathologist and chief, Registry of Tissue Reactions to Drugs, Armed Forces Institute of Pathology, Washington, D.C.

    Abstract

    The concept of anaphylaxis originates from the observations by the French physiologist Charles Richet in 1902 of the effects of actinotoxins on the blood pressure of dogs [1]. Anaphylactic shock is the classic example of the immediate type of hypersensitivity reaction; it may be defined as the failure of the peripheral circulation induced by an antigen-antibody reaction [2]. The circulatory collapse may be primary, if the circulatory reaction is the primary event, or secondary, if the circulatory collapse is the consequence of an initial respiratory insufficiency.


    Paper ID: JFS10141J

    DOI: 10.1520/JFS10141J

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    Title Anaphylactic Deaths: A Clinicopathologic Study of 43 Cases
    Symposium , 0000-00-00
    Committee E30