Journal Published Online: 01 October 1972
Volume 17, Issue 4

Anaphylactic Deaths: A Clinicopathologic Study of 43 Cases

CODEN: JFSCAS

Abstract

The concept of anaphylaxis originates from the observations by the French physiologist Charles Richet in 1902 of the effects of actinotoxins on the blood pressure of dogs [1]. Anaphylactic shock is the classic example of the immediate type of hypersensitivity reaction; it may be defined as the failure of the peripheral circulation induced by an antigen-antibody reaction [2]. The circulatory collapse may be primary, if the circulatory reaction is the primary event, or secondary, if the circulatory collapse is the consequence of an initial respiratory insufficiency.

Author Information

Delage, C
Registry of Tissue Reactions to Drugs, Armed Forces Institute of Pathology, Washington, D.C.
Irey, NS
Registry of Tissue Reactions to Drugs, Armed Forces Institute of Pathology, Washington, D.C.
Pages: 16
Price: $25.00
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Stock #: JFS10141J
ISSN: 0022-1198
DOI: 10.1520/JFS10141J