ISSN: 0022-1198
CODEN: JFSCA
Page Count: 4

L-DOPA Poisioning
Garriott, JC
The University of Texas Southwestern Medical School at Dallas and the Southwestern Institute of Forensic Sciences, Texas

Sturner, WQ
The University of Texas Southwestern Medical School at Dallas and the Southwestern Institute of Forensic Sciences, Texas

(Received 31 January 1972; accepted 24 February 1972)

Abstract

The medical therapy for Parkinson's disease, especially in younger patients, has recently included L-DOPA, the generic name for levodihydroxyphenylalanine. The prescribed therapeutic amounts of this drug have been suggested and the resulting circulating blood concentrations documented [1]. We have recently observed what appears to be the first death from an overdose of this drug, affording an opportunity to perform distribution studies on the tissues and fluids. Meprobamate and flurazepam (Dalmane) were also recovered, but in trace to therapeutic amounts.

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Paper ID: JFS10129J
DOI: 10.1520/JFS10129J
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