This standard is being balloted for withdrawal with no replacement because it has not been revised since 1997 and was developed by committee E47 for aquatic toxicity testing. When balloted for re-approval, a recommendation was recieved that it be withdrawn because there exist better and more complete standards either on the books or in development. This standard would require extensive revision to be re-approved and would duplicate effort in ISO to do so.
KeywordsAssay; Carcinogenicity; Chromosomal/genetic effects; Cloning; Cytotoxicity; Data analysis--environmental; Genetic examination; Mammalian cell mutagenicity; Metabolic activation; Mice; MLA (mouse lymphoma assay); Mutagenicity; Plating (cloning) efficiency; Quality assurance (QA)--environmental; Solubility; Spontaneous (background) mutant frequency; Test animals; THMG cleansing; Testing methods; Total growth; Toxicity/toxicology--animals;
Kenneth St John