At this time, the Standard E1280 is being balloted for withdrawal, so this work item is on hold. The purpose of this revision is to update the standard based on recommendations from international technical committee meetings, clarify definitions, and update appropriate references.
KeywordsAssay; Carcinogenicity; Chromosomal/genetic effects; Cloning; Cytotoxicity; Data analysis--environmental; Genetic examination; Mammalian cell mutagenicity; Metabolic activation; Mice; MLA (mouse lymphoma assay); Mutagenicity; Plating (cloning) efficiency; Quality assurance (QA)--environmental; Solubility; Spontaneous (background) mutant frequency; Test animals; THMG cleansing; Testing methods; Total growth; Toxicity/toxicology--animals;
Kenneth St John
Draft Under Development