Standard Historical Last Updated: Aug 16, 2017 Track Document
ASTM F750-87(2007)

Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse F0750-87R07 ASTM|F0750-87R07|en-US Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse Standard new BOS Vol. 13.01 Committee F04
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Scope

1.1 This practice covers a nonspecific, acute toxicity test used for detecting leachables from materials used in medical devices.

1.2 The liquids injected in the mouse are those obtained by Practice F 619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.

1.3 Two procedures are outlined: Method A for intravenous injection and Method B for intraperitoneal injection.

1.4 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F 748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.

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Details
Book of Standards Volume: 13.01
Developed by Subcommittee: F04.16
Pages: 3
DOI: 10.1520/F0750-87R07
ICS Code: 11.220