Standard Historical Last Updated: Dec 31, 2010 Track Document
ASTM E1202-87(2003)

Standard Guide for Development of Micronucleus Assay Standards

Standard Guide for Development of Micronucleus Assay Standards E1202-87R03 ASTM|E1202-87R03|en-US Standard Guide for Development of Micronucleus Assay Standards Standard new BOS Vol. 13.01 Committee F04
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Significance and Use

Micronucleus assays for genetic damage have been developed in many types of eucaryotic cells, both in vitro and in vivo. The occurrence of micronuclei is indicative of chromosomal damage or mitotic spindle dysfunction.

Scope

1.1 This guide covers minimal criteria which should be met by a micronucleus assay system prior to the development of an ASTM Standard or Guide for the conduct of that assay.

1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

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Details
Book of Standards Volume: 13.01
Developed by Subcommittee: F04.16
Pages: 2
DOI: 10.1520/E1202-87R03
ICS Code: 07.100.01